Albert GÜVENİŞ

Rank & Status: 

Associate Professor

Biography: 

Dr. Albert Güveniş received his PhD. degree from the Department of Electrical and Computer Engineering at Drexel University, Philadelphia, USA. He then worked as a researcher and a faculty member at the Radiology Dept. in the Hospital of the University of Pennsylvania, Philadelphia, USA in the area of Positron Emission Tomography.

Cancer Research Program

Precision medical systems and procedures as solutions to pressing effectiveness problems in cancer diagnosis and therapy.

PhD and MSc degree programs at international level for a brilliant career in a highly important area.

Those interested in applying may join our informative bi-monthly meetings (send email to pmbme@yandex.com) to have more ample information on our research program.

Courses: 

Courses are taught that include practice examples and projects for students aiming to be researchers or engineers / biomedical professionals:

BM 601 on procedures and quantitative methods for the QA of biomedical instruments, processes and systems. This course has a wide audience and is suited for those who want to practice biomedical research, clinical engineering, patient safety management in hospitals as well as design, product management, clinical application consultancy, maintenance in biomedical firms.

BM 680 on biomedical probabilistic systems modeling and design for researchers and designers.

BM 611 on molecular imaging systems (PET, SPECT-CT) for diagnosing and managing complex diseases such as cancer and Alzheimer disease.

 

 

Patents, start-ups and international work are our modes of work.

The research goal of our group is to attain high precision and effective personalized diagnostic and theranostic schemes for major diseases, in particular for cancer, by the use of several methods including molecular imaging,  systems modeling and signal/image processing . As a group one major goal is to attain high effectiveness in the diagnosis and treatment of cancer. We know what blocks the development of effective diagnostic therapeutic strategies and are working with our international partners to solve them. 

We have already achieved a number of breakthrough results which are being published in high impact journals. These results should improve detection and management effectiveness and therefore outcomes.

Memberships include AHA, IEEE and Imaging Standards Committees, Drexel University Engineering Alumni Association. Main research activities/expertise areas include computational engineering, complexity and modeling, molecular and hybrid imaging, quantitation, 3D display, radiotherapy planning, and precision in medicine.

Education: 

 

Dr. Albert Güveniş received his PhD. degree from the Department of Electrical and Computer Engineering at Drexel University, Philadelphia, USA. He then worked as a researcher and a faculty member at the Radiology Dept. in the Hospital of the University of Pennsylvania, Philadelphia, USA in the area of Positron Emission Tomography.

Experience: 

 

Faculty Assignments Drexel University, USA (Instructor) University of Pennsylvania, USA (Assistant Professor) Boğaziçi University (Associate Professor) EU and other Educational Projects Initiation and Administration of EUROPEAN UNION (EC) and other Educational Programs for continuing education. Co-training of hundreds of radiology personnel on imaging technology. 1/2 M USD FUNDING was raised.

International Collaboration in Biomedical Sectoral Projects (Major multinational project cosigned by Prof Necmi TANYOLAC who founded the institute and Dr. Joel NOBEL of ECRI, Philadelphia, USA.) Emergency Care Research Institute ECRI, Philadelphia, USA, Joint Comission of Accreditation of Healthcare Organizations, JCAHO, Chicago, USA, World Health Organization, WHO, Geneva, SWITZERLAND

International Journal & Conference Reviewer activities Within world's top 15 %. https://publons.com/author/470391/albert-guvenis#profile

Biomedical Technology Development & Comercialization - Co-inventor Patent (https://patents.google.com/patent/WO2016209184A1/en) (USA application filed) - Award (4th among 5,000+ projects by ISO - BU TTO license agreement signed for production - Referee TEYDEB, Jury and mentor for INNOVITA,  ISEK (in Collaboration with Prof Dr. Cengizhan Öztürk) HAYALET, Member, LSRC, IEEE, AHA, Drexel University Engineering Alumni Association, TC for Int Conferences, Int Standards Committees

Research Areas: 

Cancer diagnostic and therapy selection systems, Precision Medicine; 

Molecular (PET/CT - SPECT/CT) Imaging;  Modeling, Monte Carlo Simulation, Statistical Design, Statistical Decision Theory, Systems Theory, Circuit Theory, Signal and Image Processing, Quality Engineering/Metrology

 

Awards: 

Research Fellowship Drexel University

BUVAK Publication Award (A class publication)

Sleep Apnea Project 2016

Best Oral Presentation Paper Award in Budapest 2017 

Tema Award at the International IEEE EMBS Student Conference 

Key note speech invitation to IEEE sponsored meeting

News/Highlights: 

Considering short term trainning and graduate study proposals

New paper accepted by high impact Journal 2019

New publication of short papers accepted in two indexed conference proceedings and journals, 2019
 
New work appeared in Cancer Research, 2019

Int journal paper appeared in January 2019 on Lung Cancer

New thesis defenses completed for graduation (PhD and MSc) 2019 on 1) radiotherapy accuracy, 2) scintigraphic simulation and 3) tumor measurement. Recent defenses: Ayşegül Oral, Alpaslan Koç (PhD), Ayşenur Yüksel, Ezgi Kara.

Abstract on eye performance accepted by International Agrricultural, Biological & Life science Conference -

Invited speaker at International simulation conference - Invited speaker at International IEEE EMBS conference -

Int Journal paper appeared on issue of July 2018 -

New referee / reviewer assignments  - Our paper won the best paper award in Budapest  This year's conference: http://www.iscsic.org/ - Our paper on portable displays performance has been presented in Bangkok, Thailand at this year's international medical physics congress - Int Journal research article on tumor recognition has initial acceptance  - Paper on Chronic Disease Quantification has been accepted to be presented at Biomath  South Africa - New Int. PET imaging standard work released ( (Contribution) - Our invention has been selected by ITU among 5000+ participants for a major innovation award. - Presented new algorithm for nodule segmentation in Las Vegas USA  - Presented new scheme for Alzheimer Detection in the World Congress in Toronto CANADA - Presented tumor delineation and characterization poster in Biomed Eng Conference in San Antonio, USA - PATENT application co-filed for new invention in June 2016 - Credited by PUBLONS for international journal review work - Work on new tumor delineation algorithm presented in Birmingham, UK as a poster and included in the J Nucl Med Radiat Therapy - Contribution to the international complex dynamic systems workshop - New work accepted by the IEEE transactions

Research Projects: 

 

Affiliations with major cancer research laboratories - High sensitivity early detection of cancerous tumours in Nuclear Medicine Imaging (Positron Emission Tomography PET and Single Photon Emission Computed Tomography, SPECT) - Tumour Delineation and Radiotherapy planning accuracy optimization in order to minimize the inflicted damage to the patient and maximize the curing effect - PET and CT Radiomics & Radiogenomics - Medical image quality optimization and assessment in Radiology & Nuclear Medicine for critical clinical applications (e.g. lung cancer) Core Research Team: Albert Guvenis, Didar Talat, Alpaslan Koc, Niyazi Erturk, Dilara Turegun; + Many other students.

Local and worldwide collaborators: We are often hosting international researchers (e.g. from the US) in our premises for enriching our research team. Those researchers who finish an innovative project are often solicited by overseas research institutions mainly in the US. Research Partnership Sollicitations should be addressed to Prof INCE. Collaborations are being conducted and considered in order to enrich our research studies and goals.

(From NCI)

Publications: 

Selected Conference Abstracts and Proceedings

Balta S., Guvenis, A.; “Robust Design of a Breast Scintigraphy Collimator Using Monte Carlo Simulation and Response Surface Method”, EANM 07 Annual Congress of the European Association of Nuclear Medicine, October 13-17, 2007,Copengagen, Denmark

Talat, D., A. Guvenis; A., “The Effect of Crystal Thickness on Spatial Resolution and Linearity for PET Detectors using ANN Based Positioning Algorithms: A Simulation Study”, EANM 07 Annual Congress of the European Association of Nuclear Medicine, October 13-17, 2007,Copengagen, Denmark

Berk, S., Talat, D., Guvenis; A. “A Look-Up-Table Based Positioning Algorithm for Small Organ Positron Emission Tomography”, EANM 07 Annual Congress of the European Association of Nuclear Medicine, October 13-17, 2007,Copengagen, Denmark

Guvenis, A., Guven, E., Haktan, M., Talat, D. “Web based system for bone age assessment”, Proceedings of 6th International Conference on Information and Communication Technologies in Health, 11-13 July 2008, Samos, Greece. pp 281-286. Published by National and Kapodistrian University of Athens, Greece, ISBN: 978-960-466-013-1

Demirci, U., Guvenis, A., “An Internet based System for Monitoring Patients and Relatives Satisfaction rates in Health Services”, Proceedings of the 6th International Conference on Information and Communication Technologies in Health, 11-13 July 2008, Samos; Grece. pp 236-247. Published by National and Kapodistrian University of Athens, Greece, ISBN: 978-960-466-013-1

Talat D, Guvenis A., “Comparison of Positioning Algortihms for a PET Detector: A Simulation Study”, Eur J Nucl Med Mol Imaging (2009) 36 (Suppl 2):S412

Talat D, Guvenis A., PEM Görüntüleme için Yapay Sinir Ağları Temelli Bir Pozisyonlama Algoritması 14. Biyomedikal Mühendisliği Ulusal Toplantısı, 20-24 Mayıs 2009, İzmir

Metin Yildiz, Albert Guvenis, Esra Guven, Didar Talat, Implementation and Evaluation of Computer Assisted Bone Age Assessment Methods, 7th ICICTH Samos, Greece, 16-18 July 2009

Enes Ozkalay, Albert Guvenis, Didar Talat, “Computerized Bone Age Assessment for Young Children”, 8th ICICTH Samos, Greece, 15-17 July 2010

Talat, D., S. Balta Beylergil and A. Guvenis, “Optimal Experimentation for Nuclear Medicine Imaging System Design,” 2012 Nuclear Science Symposium, Medical Imaging Conference & Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Anaheim, California, USA, 29 October – 3 November, 2012.

Talat, D. and A. Guvenis, “Design and Evaluation of a Breast Specific Collimator Using Response Surface Methodology and Monte Carlo Simulations,” 2013 Nuclear Science Symposium, Medical Imaging Conference & Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Seoul, Korea, 26 October – 2 November, 2013

Albert Guvenis, “Statistical Design of Biomedical Devices and Systems”, Proceedings IW BBIO 2013 International Work-Conference on Bioinformatics and Biomedical Engineering, Granada March 18-20 2013, ISBN GR 489/2013 pp: 457-464

Albert Guvenis, Alpaslan Koc, "Optimizing Delineation Accuracy of Tumors in PET for Radiotherapy Planning using Blind Deconvolution", International Conference on Radiation Protection in Medicine in Medicine, Varna Bulgaria, May 30 - June 2, 2014,

Cankaya E., Guvenis A., "Mutual Information Based Template Matching Method for the Computer Aided Diagnosis of Alzheimer Disease", IUPESM World Congress on Medical Physics and Biomedical Engineering, Toronto Canada; 06/2015

Damgacı, A., Guvenis A. Planar and Spect Study Optimization for 99mTc‐MAA Studies Using Monte Carlo Simulation International Workshop on Theoretical and Experimental Studies in Nuclear Applications and Technology TESNAT 2015; 04/2015

Tunali, I, Guvenis, A., A Fusion Method for Pulmonary Nodule Segmentation in Chest CT Image Sets, Proceedings of the IEEE International Conference on Biomedical Health Informatics, Las Vegas, USA, 24-27 February, 2016

Ozturk N, , Kaygusuz H, Guvenis A., "Can Pseudocolor Improve Performance On Portable And Mobile Devices Displays For High Detail, Low Contrast Medical Images at Daylight Conditions?", 22nd International Conference on Medical Physics, Bangkok, Thailand, 2016.

Guvenis, Albert. "Defining Process Capability Indices for Time Series Data from Patients with Chronic Diseases." Biomath Communications Supplement 4.1 (2017) Biomath 2017 Conference in South Africa, 2017.

Koç, Alpaslan, and Albert Güvenış. "Implementation method in blind deconvolution based tumor segmentation using simulated PET images." Medical Technologies National Congress (TIPTEKNO), 2017. IEEE, 2017 (Proceedings).

Sultan Damgaci, Heman Chao, Marni D. Uger, Arig Ibrahim-Hashim, Eunjung Kim, Pedro Pedro M. Enriquez‐Navas, Dominique Abrahams, Alexander R. Anderson, Albert Guvenis, Robert J. Gillies. Improving survival in pancreatic cancer using Doxorubicin in combination with L-DOS47 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1231.

Selected Journal Publications

Fischl, R., Halpin, T.F., Guvenis, A.: "The application of decision theory to contingency selection ", IEEE Transactions on CAS-29 11:712713, 1982.

Muehllehner, G., Karp, J.S. and Guvenis, A.: "A Method for reconstructing Images from Data Obtained with a Hexagonal Bar Positron Camera", IEEE Transactions on Medical Imaging, Vol. MI-4, No: 3 September 1985.

Turoglu, T., Demir, M., Guvenis, A., UrgancIoglu, I., “Detectability of lesions in Nuclear Medicine", Turkish Journal of Nuclear Medicine, 2, 30-36, 1993.

Guvenis, A., Ayan Z., Serin Ö.: “Copy Management in a Shared Care Environment using the Internet”, Topics in Health Information Management, Volume 18, No.2, 39-45, November, 1997.

Guvenis, A., Yilmaz, A., “Quality Improvement of Medical Imaging and Tele-Radiology Procedures using Computer Simulation”, J.Q.L.R. The official International E.C.Qua.L. Journal for Quality of Life Research, Vol 3, Issue 2 Suppl 1, pp 150:153 May-June 2005

Guvenis, A., Guven, A., Haktan, M., Talat, D. “Web based system for bone age assessment”, The Journal on Information Technology in Healthcare, Volume 6, issue: 5, Oct 01, 2008

Metin Yildiz, Albert Guvenis, Esra Guven, Didar Talat and Mahmut Haktan, “Implementation and Statistical Evaluation of a Web-Based Software for Bone Age Assessment”, JOURNAL OF MEDICAL SYSTEMS, Volume 35, Number 6 (2011), 1485-1489, DOI: 10.1007/s10916-009-9425-z

Guvenis, A., Koc A., "Optimizing Delineation Accuracy of Tumors in PET for Radiotherapy Planning using Blind Deconvolution", International Conference on Radiation Protection in Medicine in Medicine, May 30 - June 2, 2014, Varna Bulgaria, Abstract published in Medical Physics International Journal, vol.2, No.1, 224, 2014

Koc, A., Guvenis, A., "Effect Of Image Resampling On Tumour Volume Estimation Accuracy In Positron Emission Tomography Images Restored Via the Blind Deconvolution Method", International Conference on Medical Physics August 03-05, 2015 Birmingham, UK, Poster published at At J Nucl Med Radiat Ther, Volume: 6, DOI: 10.4172/2155-9619.S1.003

Albert Guvenis, Alpaslan Koc, "Optimizing Delineation Accuracy of Tumors in PET for Radiotherapy Planning using Blind Deconvolution", Journal of Radiation Protection Dosimetry, Vol 165, 1-4 pp 495-498, 2015.

D. Talat; A. Guvenis, Design and Evaluation of a Breast-Specific Collimator Using Response Surface Methodology and Monte Carlo Simulations, IEEE Transactions on Nuclear Science, 2016, Volume: 63, Issue: 1, Pages: 98 - 107, DOI: 10.1109/TNS.2015.2484070

Tunali, I., Stringfield, O., Guvenis, A., Wang, H., Liu, Y., Balagurunathan, Y., ... & Schabath, M. B. (2017). Radial gradient and radial deviation radiomic features from pre-surgical CT scans are associated with survival among lung adenocarcinoma patients. Oncotarget, 8(56), 96013.

Damgaci, S., Ibrahim‐Hashim, A., Enriquez‐Navas, P. M., Pilon‐Thomas, S., Guvenis, A., & Gillies, R. J. (2018). Hypoxia and acidosis: immune suppressors and therapeutic targets. Immunology, Volume 154, Issue 3 pages 354-362 (July 2018).

Tunali, Ilke, Jhanelle E. Gray, Jin Qi, Mahmoud Abdalah, Daniel K. Jeong, Albert Guvenis, Robert J. Gillies, and Matthew B. Schabath. "Novel clinical and radiomic predictors of rapid disease progression phenotypes among lung cancer patients treated with immunotherapy: An early report." Lung Cancer 129 (2019): 75-79.

Sultan Damgaci, Heman Chao, Marni D. Uger, Arig Ibrahim-Hashim, Eunjung Kim, Pedro Pedro M. Enriquez‐Navas, Dominique Abrahams, Alexander R. Anderson, Albert Guvenis and Robert J. Gillies, "Improving survival in pancreatic cancer using Doxorubicin in combination with L-DOS47", Cancer Research Volume 79, Issue 13 Supplement, pp. 1231 (Abstract)

More papers in the process of being submitted.

Published Books

Erturk, S., Guvenis, A., Ternar, O., Detector Design for Animal Positron Emission Tomography Systems, Lambert Academic Publishing AG & Co. KG Saarbrücken, ISBN-13: 978-3838346281, 2010

Turegun, K.D., A Computerized System for Tracking Clinical Engineering Outcomes: using Statistical Process Control, LAP LAMBERT Academic Publishing AG & Co. KG Saarbrücken, ISBN-13: 978-3845407661, 2011

Published Booklets

Guvenis, A.: "Proper Darkroom and Photographic Quality Control Techniques", Training Course Booklet, Biomedical Engineering Institute, Bogazici University,

Reviewer for: 

Several journals and international conferences

https://publons.com/author/470391/albert-guvenis#profile

Contact: 

E-Mail

Phone Number: 

+90 216 516 3464

E-Mail: 
guvenis@boun.edu.tr
Courses: 

 

BM 611 Nuclear Medicine (Molecular Imaging) Instrumentation -

BM 601 Quality Assurance Principles for Biomedical Engineers -

BM 680 Special Topics: Biomedical Probabilistic Systems Modeling and Design